ANTI - CANCER DRUGS
1. Alkylating Agents
Nitrogen Mustards: Cyclophosphamide, Ifosfamide, Chlorambucil, Melphalan
Nitrosoureas: Carmustine (BCNU), Lomustine (CCNU)
Alkyl Sulfonates: Busulfan
Triazines: Dacarbazine, Temozolomide
Ethylenimines: Thiotepa
2. Platinum-Based Drugs
Cisplatin
Carboplatin
Oxaliplatin
3. Antimetabolites
Folate Antagonists: Methotrexate, Pemetrexed
Pyrimidine Analogues: Fluorouracil (5-FU), Capecitabine, Cytarabine, Gemcitabine
Purine Analogues: Mercaptopurine, Thioguanine, Fludarabine, Cladribine
4. Anti-Tumor Antibiotics
Anthracyclines: Doxorubicin, Daunorubicin, Epirubicin, Idarubicin
Chromomycins: Dactinomycin
Miscellaneous: Bleomycin, Mitomycin
5. Topoisomerase Inhibitors
Topoisomerase I Inhibitors: Irinotecan, Topotecan
Topoisomerase II Inhibitors: Etoposide, Teniposide
6. Mitotic Inhibitors
Vinca Alkaloids: Vincristine, Vinblastine, Vinorelbine
Taxanes: Paclitaxel, Docetaxel, Cabazitaxel
7. Hormonal Agents
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen, Raloxifene
Aromatase Inhibitors: Anastrozole, Letrozole, Exemestane
Anti-Androgens: Flutamide, Bicalutamide, Enzalutamide
LHRH Agonists/Antagonists: Leuprolide, Goserelin, Degarelix
Progestins: Megestrol acetate
8. Targeted Therapy
Monoclonal Antibodies:
Anti-HER2: Trastuzumab, Pertuzumab
Anti-CD20: Rituximab, Obinutuzumab
Anti-VEGF: Bevacizumab
Anti-EGFR: Cetuximab, Panitumumab
Tyrosine Kinase Inhibitors:
BCR-ABL Inhibitors: Imatinib, Dasatinib, Nilotinib
EGFR Inhibitors: Erlotinib, Gefitinib, Osimertinib
ALK Inhibitors: Crizotinib, Ceritinib, Alectinib
VEGFR Inhibitors: Sunitinib, Sorafenib, Axitinib
mTOR Inhibitors: Everolimus, Temsirolimus
Proteasome Inhibitors: Bortezomib, Carfilzomib
9. Immunotherapy
Checkpoint Inhibitors:
PD-1 Inhibitors: Pembrolizumab, Nivolumab
PD-L1 Inhibitors: Atezolizumab, Durvalumab, Avelumab
CTLA-4 Inhibitors: Ipilimumab
CAR-T Cell Therapy: Tisagenlecleucel, Axicabtagene ciloleucel
10. Other Agents
Proteasome Inhibitors: Bortezomib, Carfilzomib
Histone Deacetylase Inhibitors (HDAC inhibitors): Vorinostat, Romidepsin
PARP Inhibitors: Olaparib, Niraparib, Rucaparib
BCL-2 Inhibitors: Venetoclax
Immunomodulatory Drugs (IMiDs): Thalidomide, Lenalidomide, Pomalidomide
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